multicomponent preparation of highly functionalized piperidines using fecl3.6h2o as an efficient catalyst

Multicomponent preparation of highly functionalized piperidines using FeCl3.6H2O as an efficient catalyst

FeCl3.6H2O was used as an efficient catalyst for the synthesis of highly functionalized piperidines via a one-pot five-component reaction of aromatic amines, aromatic aldehydes and β-keto esters in EtOH at room temperature. The remarkable advantages offered by this method are good yields, simple procedure, short reaction times, no need to column chromatography and easy work-up. The structures o...

Multicomponent preparation of highly functionalized piperidines using FeCl3.6H2O as an efficient catalyst

FeCl3.6H2O was used as an efficient catalyst for the synthesis of highly functionalized piperidines via a one-pot five-component reaction of aromatic amines, aromatic aldehydes and β-keto esters in EtOH at room temperature. The remarkable advantages offered by this method are good yields, simple procedure, short reaction times, no need to column chromatography and easy work-up. The structures o...

Trichloroacetic Acid as an Efficient Catalyst for One-pot Synthesis of Highly Functionalized Piperidines via multi-component Reaction

Trichloroacetic Acid (TCA) was used as an efficient catalyst for the synthesis of highly functionalized piperidines via a one-pot five-component reaction of aromatic amines, aromatic aldehydes and β-keto esters in MeOH at room temperature. The remarkable advantages offered by this method are good yields, simple procedure, short reaction times, no need to column chromatography and an easy wo...

One pot, Five-component Synthesis of Functionalized Piperidines Using Zn(OAc)2.2H2O as a Highly Efficient Catalyst

A convenient synthetic route for the synthesis of biologically active functionalized piperidines usingZn(OAc)2.2H2O as a highly efficient catalyst via five-component reaction of aromatic aldehydes,anilines and β-ketoesters at ambient temperature has studied. Mild reaction conditions, simplicity ofoperation and work-up procedures with no necessity of chromatographic purification steps, theavaila...

SbCl3 as an Efficient Catalyst for the One-pot Synthesis of Highly Substituted Piperidines

Highly substituted piperidines were synthesized via the condensation of aromatic aldehydes and aromatic amines with β-ketoesters in the presence of antimony(III) chloride at ambient condition. This reaction has any advantages such as easy work-up, clean procedure, and good yields.

fecl3•6h2o as efficient catalyst for one-pot synthesis of highly functionalized piperidines